Rare Pediatrics News
5 Facts you should know about
RNA interference
1
RNAi is a natural biological process that regulates gene expression by “interfering” with messenger RNA (mRNA)
2
RNAi is mediated by many endogenous RNAs [e.g. piwi-interacting RNA (piRNA), microRNA (miRNA), and small interfering RNA (siRNA)
3
RNAi offers selective gene targeting in a species-specific manner
4
RNAi therapeutics mimic this process by delivering designed small interfering RNAs (siRNAs) that bind to target disease-causing mRNA and guide their destruction
5
Although it has similarities to antisense technology, RNAi has evolved into a distinct platform for modifying how RNA can be “interrupted” to improve cell function
Rare Pediatrics News
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