Rare Pediatrics News
Spotlight On
Kindler syndrome
Kindler syndrome is a rare type of epidermolysis bullosa, a group of inherited conditions that cause fragile and blistering skin
Prevalence
Unknown
Age of Onset
ICD-10
Q81.8
Inheritance
Autosomal dominant
Autosomal recessive
Mitochondrial/Multigenic
X-linked dominant
X-linked recessive
5 Facts you should know
FACT
Kindler syndrome causes skin to blister beginning in early infancy
FACT
Infants and young children with Kindler syndrome have a tendency to blister with minor trauma
FACT
Other symptoms may include photosensitivity, poikiloderma, hyperkeratosis
FACT
The condition can also affect the moist lining of the mouth, eyes, esophagus, intestines, genitals, and urinary system
FACT
Patients with Kindler syndrome have an increased risk for squamous cell carcinoma
Interest over time
Common signs & symptoms
Abnormal blistering of the skin
Aplasia/Hypoplasia of the skin
Cheilitis
Cutaneous photosensitivity
Erythema
Palmoplantar keratoderma
Poikiloderma
Current treatments
Currently, there is no cure or established treatment for Kindler syndrome. Therefore, the goals of management are to treat the symptoms and prevent complications.